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Access to RNA Encapsidated in the Nucleocapsid of Vesicular Stomatitis Virus

23 Dec 2010

Abstract excerpt

The genomic RNA of negative-strand RNA viruses, such as vesicular stomatitis virus (VSV), is completely enwrapped by the nucleocapsid protein (N) in every stage of virus infection. During viral transcription/replication, however, the genomic RNA in the nucleocapsid must be accessible by the virus-encoded RNA-dependent RNA polymerase in order to serve as the template for RNA synthesis. With the VSV nucleocapsid...

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PMID: 21177817
DOI: 10.1128/jvi.01927-10

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