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Article

Genetic aspects of the antiphospholipid syndrome: An update.

Autoimmunity reviews - 1 May 2016

Sebastiani Gian Domenico, Iuliano Annamaria, Cantarini Luca, Galeazzi Mauro

Abstract excerpt

Studies on the immunogenetic predisposition to antiphospholipid syndrome (APS) and on other non-genetic and epigenetic factors are summarised and discussed. Family studies suggest a genetic predisposition to APS. It appears that this genetic predisposition is in part accounted for by the HLA system, the most consistent associations being those with DR4 and DRw53. Furthermore, it appears that lupus anticoagulant...

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Identifiers

PMID: 26804759
DOI: 10.1016/j.autrev.2016.01.005

Genes

STAT4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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