Glucose restriction induces transient G2 cell cycle arrest extending cellular chronological lifespan

Abstract excerpt

While glucose is the fundamental source of energy in most eukaryotes, it is not always abundantly available in natural environments, including within the human body. Eukaryotic cells are therefore thought to possess adaptive mechanisms to survive glucose-limited conditions, which remain unclear. Here, we report a novel mechanism regulating cell cycle progression in response to abrupt changes in extracellular...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diabetes and associated disorders
• Share to Metabolism, Diabetes, and Cancer
• Share to Pancreatic function and diabetes