Article
CCL2 gene polymorphism is associated with post-transplant diabetes mellitus.
International immunopharmacology - 1 Mar 2016
Dabrowska-Zamojcin Ewa, Romanowski Maciej, Dziedziejko Violetta, Maciejewska-Karlowska Agnieszka, Sawczuk Marek, Safranow Krzysztof, Domanski Leszek, Pawlik Andrzej
Abstract excerpt
Post-transplant diabetes mellitus (PTDM) is a common complication after solid organ transplantation, especially in recipients treated with calcineurin inhibitors. Previous studies suggest that chronic inflammation and chemokines play an important role in the pathogenesis of diabetes. Single-nucleotide polymorphisms (SNPs) can increase or decrease transcriptional activity and can change the production of...
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