Article
Osteogenic markers are reduced in bone-marrow mesenchymal cells and femoral bone of young spontaneously hypertensive rats.
Life sciences - 1 Feb 2016
Landim de Barros Thamine, Brito Victor Gustavo Balera, do Amaral Caril Constante Ferreira, Chaves-Neto Antonio Hernandes, Campanelli Ana Paula, Oliveira Sandra Helena Penha
Abstract excerpt
AIMS: Spontaneously hypertensive rats (SHR) and normotensive rats (W) has significant changes in bone metabolism. The purpose of this study was to investigate whether, the genetic predisposition, is sufficient to induce changes in the osteoblast differentiation and osteogenic markers in the BMSCs or in the femoral bone. For this we use young SHR rats without hypertension, but, with genetic predisposition in...
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