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Article

Circulating mesenchymal stem cells with abnormal osteogenic differentiation in patients with osteoporosis

29 Oct 2009

Abstract excerpt

OBJECTIVE: While the role of osteoclasts in bone loss has been well investigated, the involvement of osteoblast-lineage cells has not been completely elucidated. Several genes contribute to normal osteoblastic differentiation from mesenchymal stem cells (MSCs), but an understanding of their role in the pathogenesis of osteoporosis is still lacking. The present study was undertaken to evaluate a possible...

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PMID: 19877060
DOI: 10.1002/art.24884

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