Article
The dynamic three-dimensional culture of islet-like clusters in decellularized liver scaffolds.
Cell and tissue research - 1 Jul 2016
Zhou Pengcheng, Guo Yibing, Huang Yan, Zhu Mingyan, Fan Xiangjun, Wang Lei, Wang Yao, Zhu Shajun, Xu Tianxing, Wu Di, Lu Yuhua, Wang Zhiwei
Abstract excerpt
Diabetes mellitus is a worldwide metabolic disease which constitutes a major threat to human health. Stem cells with the ability to differentiate into insulin-producing cells (IPCs) could provide unlimited sources of transplanted cells and solve allogeneic rejection problems. The decellularized scaffolds could provide IPCs with tissue microarchitecture and intact vascular systems. The goal of this study was to...
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