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Article

Effects of CCN3 on rat cartilage endplate chondrocytes cultured under serum deprivation in vitro.

Molecular medicine reports - 1 Mar 2016

Ding Lei, Wu Jingping, Li Defang, Wang Houlei, Zhu Bin, Lu Wei, Xu Guoxiong

Abstract excerpt

The presence of apoptotic cells and loss of extracellular matrix (ECM) are common characteristics of degenerated cartilage endplates (CEPs). In addition, therapeutic efficacy is hampered by an incomplete understanding regarding the mechanisms underlying CEP homeostasis and degeneration. The CCN proteins have recently emerged as important regulators of cell‑ECM interactions, and have been identified as key...

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Share to Apoptosis
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Share to Cartilage, Articular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Culture Media, Serum-Free

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Share to Rats, Sprague-Dawley

Source

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Identifiers

PMID: 26795879
DOI: 10.3892/mmr.2016.4803
PMCID: PMC4768995

Genes

CCN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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