Article
Efficient and specific inhibition of plant microRNA function by anti-microRNA oligonucleotides (AMOs) in vitro and in vivo.
Plant cell reports - 1 Apr 2016
He Lian, Xie Munan, Huang Jianhua, Zhang Tianyuan, Shi Suhua, Tang Tian
Abstract excerpt
KEY MESSAGE: Anti-microRNA oligonucleotides (AMOs) are efficient and sequence-specific inhibitors of plant miRNA function both in vitro and in vivo. MicroRNAs (miRNAs) are small non-coding RNAs that play critical roles in developmental and physiological processes in plants and animals. Although miRNA knockdown by chemically modified antisense oligonucleotides prevails in animal and therapeutic studies, no such...
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