Article
Genomic variation in the porcine immunoglobulin lambda variable region.
Immunogenetics - 1 Apr 2016
Guo Xi, Schwartz John C, Murtaugh Michael P
Abstract excerpt
Production of a vast antibody repertoire is essential for the protection against pathogens. Variable region germline complexity contributes to repertoire diversity and is a standard feature of mammalian immunoglobulin loci, but functional V region genes are limited in swine. For example, the porcine lambda light chain locus is composed of 23 variable (V) genes and 4 joining (J) genes, but only 10 or 11 V and 2 J...
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