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Article

Validation of a DNA methylation HPV triage classifier in a screening sample.

International journal of cancer - 1 Jun 2016

Lorincz Attila T, Brentnall Adam R, Scibior-Bentkowska Dorota, Reuter Caroline, Banwait Rawinder, Cadman Louise, Austin Janet, Cuzick Jack, Vasiljević Natasa

Abstract excerpt

High-risk human papillomavirus (hrHPV) DNA tests have excellent sensitivity for detection of cervical intraepithelial neoplasia 2 or higher (CIN2+). A drawback of hrHPV screening, however, is modest specificity. Therefore, hrHPV-positive women might need triage to reduce adverse events and costs associated with unnecessary colposcopy. We compared the performance of HPV16/18 genotyping with a predefined DNA...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26790008
DOI: 10.1002/ijc.30008
PMCID: PMC4832297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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