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Enterovirus D68 receptor requirements unveiled by haploid genetics

19 Jan 2016

Abstract excerpt

Enterovirus D68 (EV-D68) is an emerging pathogen that can cause severe respiratory disease and is associated with cases of paralysis, especially among children. Heretofore, information on host factor requirements for EV-D68 infection is scarce. Haploid genetic screening is a powerful tool to reveal factors involved in the entry of pathogens. We performed a genome-wide haploid screen with the EV-D68 prototype...

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PMID: 26787879
DOI: 10.1073/pnas.1524498113

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