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Article

Linkage between the mechanisms of thrombocytopenia and thrombopoiesis.

Blood - 10 Mar 2016

Eto Koji, Kunishima Shinji

Abstract excerpt

Thrombocytopenia is defined as a status in which platelet numbers are reduced. Imbalance between the homeostatic regulation of platelet generation and destruction is 1 potential cause of thrombocytopenia. In adults, platelet generation is a 2-stage process entailing the differentiation of hematopoietic stem cells into mature megakaryocytes (MKs; known as megakaryopoiesis) and release of platelets from MKs (known...

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Source

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Identifiers

PMID: 26787737
DOI: 10.1182/blood-2015-07-607903
PMCID: PMC4786834

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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