Article
Postnatal Hematopoiesis and Gut Microbiota in NOD Mice Deviate from C57BL/6 Mice.
Journal of diabetes research - 1 Jan 2016
Damlund Dina Silke Malling, Metzdorff Stine Broeng, Hasselby Jane Preuss, Wiese Maria, Lundsager Mia, Nielsen Dennis Sandris, Buschard Karsten Stig, Hansen Axel Kornerup, Frøkiær Hanne
Abstract excerpt
Neonatal studies in different mouse strains reveal that early life colonization affects the development of adaptive immunity in mice. The nonobese diabetic (NOD) mouse spontaneously develops autoimmune diabetes, but neonatal studies of NOD mice are lacking. We hypothesized that NOD mice deviate from another much used mouse strain, C57BL/6, with respect to postnatal microbiota and/or hematopoiesis and compared...
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