Article
Interleukin 10 gene promoter polymorphisms are associated with chronic periodontitis.
Journal of clinical periodontology - 1 Jun 2004
Scarel-Caminaga Raquel M, Trevilatto Paula C, Souza Ana P, Brito Rui B, Camargo Luis E A, Line Sergio R P
Abstract excerpt
BACKGROUND: Chronic periodontitis (CP) is characterized by an inflammation in the supporting tissues of the teeth caused primarily by bacterial infection. Interleukin 10 (IL10) is an anti-inflammatory cytokine whose genetic polymorphisms may influence the expression of the protein. OBJECTIVE: In this study we investigated the hypothesis that single-nucleotide polymorphisms (SNPs) in the promoter of IL10 gene...
Topics
- Adenine
- Adult
- Chronic Disease
- Cytosine
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Guanine
- Haplotypes
- Heterozygote
- Humans
