Article
Synaptosomal Protein of 25 kDa (Snap25) Polymorphisms Associated with Glycemic Parameters in Type 2 Diabetes Patients.
Journal of diabetes research - 1 Jan 2016
Al-Daghri Nasser M, Costa Andrea S, Alokail Majed S, Zanzottera Milena, Alenad Amal M, Mohammed Abdul Khader, Clerici Mario, Guerini Franca R
Abstract excerpt
A possible role of Snap25 polymorphisms in type 2 diabetes mellitus (T2DM) was evaluated by analyzing three SNPs within intron 1 in a region known to affect the gene expression in vitro. Genomic DNA from 1019 Saudi individuals (489 confirmed T2DM and 530 controls) was genotyped for SNPs rs363039, rs363043, and rs363050 in Snap25 using the TaqMan Genotyping Assay. Significantly higher levels of fasting glucose and...
Read the complete abstract on PubMed