Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

hnRNPA2/B1 activates cyclooxygenase‐2 and promotes tumor growth in human lung cancers

30 Nov 2015

Abstract excerpt

Cyclooxygenase-2 (COX-2) is highly expressed in tumor cells and has been regarded as a hallmarker for cancers, but the excise regulatory mechanism of COX-2 in tumorigenesis remains largely unknown. Here, we pulled down and identified a novel COX-2 regulator, heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1), which could specifically bind to COX-2 core promoter and regulate tumor growth in non-small-cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Inflammatory mediators and NSAID effects
Share to NF-κB Signaling Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26774881
DOI: 10.1016/j.molonc.2015.11.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

hnRNPA2/B1 activates cyclooxygenase‐2 and promotes tumor growth in human lung cancersPMID 26774881Read ↗

TFAP2B overexpression contributes to tumor growth and progression of thyroid cancer through the COX-2 signaling pathwaySemantic proximity Read ↗

TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signalingSemantic proximity Read ↗

NAP1L1 Interacts with Hepatoma-Derived Growth Factor to Recruit C-Jun Inducing Breast Cancer GrowthSemantic proximity Read ↗

Polymorphisms of COX/PEG2 pathway-related genes are associated with the risk of lung cancer: A case-control study in China.Semantic proximity Read ↗

CNBP controls tumor cell biology by regulating tumor‐promoting gene expressionSemantic proximity Read ↗

ZRANB1 Drives Hepatocellular Carcinoma Progression through SP1-LOXL2 AxisSemantic proximity Read ↗

Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cellsSemantic proximity Read ↗

HNRNPA2B1-mediated m6A modification of lncRNA MEG3 facilitates tumorigenesis and metastasis of non-small cell lung cancer by regulating miR-21-5p/PTEN axisSemantic proximity Read ↗

EYA2 promotes lung cancer cell proliferation by downregulating the expression of PTENSemantic proximity Read ↗

Splicing factor hnRNPA2B1 contributes to tumorigenic potential of breast cancer cells through STAT3 and ERK1/2 signaling pathwaySemantic proximity Read ↗

Role of Cyclooxygenase-2 in Head and Neck Tumorigenesis.Semantic proximity Read ↗

SIRT2 suppresses non-small cell lung cancer growth by targeting JMJD2ASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.