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Article

HRAS mutation prevalence and associated expression patterns in pheochromocytoma.

Genes, chromosomes & cancer - 1 May 2016

Stenman Adam, Welander Jenny, Gustavsson Ida, Brunaud Laurent, Bäckdahl Martin, Söderkvist Peter, Gimm Oliver, Juhlin C Christofer, Larsson Catharina

Abstract excerpt

Pheochromocytomas (PCC) and abdominal paragangliomas (PGL) display a highly diverse genetic background and recent gene expression profiling studies have shown that PCC and PGL (together PPGL) alter either kinase signaling pathways or the pseudo-hypoxia response pathway dependent of the genetic composition. Recurrent mutations in the Harvey rat sarcoma viral oncogene homolog (HRAS) have recently been verified in...

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Source

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Identifiers

PMID: 26773571
DOI: 10.1002/gcc.22347
PMCID: PMC4794776

Genes

HRAS
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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