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Article

Screening a yeast library of temperature-sensitive mutants reveals a role for actin in tombusvirus RNA recombination.

Virology - 1 Feb 2016

Prasanth K Reddisiva, Kovalev Nikolay, de Castro Martín Isabel Fernández, Baker Jannine, Nagy Peter D

Abstract excerpt

Genetic recombination in RNA viruses drives the evolutionary arms race with host's antiviral strategies and recombination also facilitates adaptation of viruses to new hosts. In this paper, the authors used tombusvirus and a temperature-sensitive (ts) mutant library of yeast to identify 40 host proteins affecting viral recombination in yeast model host. Subsequent detailed analysis with two identified...

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Identifiers

PMID: 26773384
DOI: 10.1016/j.virol.2015.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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