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Article

Characterizing mutation-treatment effects using clinico-genomics data of 78,287 patients with 20 types of cancers.

Nature communications - 30 Dec 2024

Liu Ruishan, Rizzo Shemra, Wang Lisa, Chaudhary Nayan, Maund Sophia, Garmhausen Marius Rene, McGough Sarah, Copping Ryan, Zou James

Abstract excerpt

Evaluating the effectiveness of cancer treatments in relation to specific tumor mutations is essential for improving patient outcomes and advancing the field of precision medicine. Here we represent a comprehensive analysis of 78,287 U.S. cancer patients with detailed somatic mutation profiling integrated with treatment and outcomes data extracted from electronic health records. We systematically identified 776...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39738052
DOI: 10.1038/s41467-024-55251-5
PMCID: PMC11686316

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