TP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation.

doi:10.1111/bjh.13912

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Article

TP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation.

British journal of haematology - 1 Mar 2016

Middeke Jan M, Herold Sylvia, Rücker-Braun Elke, Berdel Wolfgang E, Stelljes Matthias, Kaufmann Martin, Schäfer-Eckart Kerstin, Baldus Claudia D, Stuhlmann Reingard, Ho Anthony D, Einsele Hermann, Rösler Wolf, Serve Hubert, Hänel Mathias, Sohlbach Kristina, Klesse Christian, Mohr Brigitte, Heidenreich Falk, Stölzel Friedrich, Röllig Christoph, Platzbecker Uwe, Ehninger Gerhard, Bornhäuser Martin, Thiede Christian, Schetelig Johannes

Abstract excerpt

Treatment success in patients with acute myeloid leukaemia (AML) is heterogeneous. Cytogenetic and molecular alterations are strong prognostic factors, which have been used to individualize treatment. Here, we studied the impact of TP53 mutations on the outcome of AML patients with adverse cytogenetic risk treated with allogeneic haematopoietic stem cell transplantation (HSCT). Samples of 97 patients with AML and...

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PMID: 26771088
DOI: 10.1111/bjh.13912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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