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Article

Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Zeichner Simon Blechman, Alghamdi Sarah, Elhammady Gina, Poppiti Robert John

Abstract excerpt

BACKGROUND: The response to treatment and overall survival (OS) of patients with acute myeloid leukemia (AML) is variable, with a median ranging from 6 months to 11.5 years. TP53 is associated with old age, chemotherapy resistance, and worse OS. Using genetic sequencing, we set out to look at our own experience with AML, and hypothesized that both TP53 mutations and SNPs at codon 72 would mimic the literature by...

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Identifiers

PMID: 24641375
DOI: 10.7314/apjcp.2014.15.4.1603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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