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Article

Association between ABCA1 gene polymorphisms and the therapeutic response to donepezil therapy in Han Chinese patients with Alzheimer's disease.

Brain research bulletin - 1 Jun 2018

Lu Jin, Fu Jianliang, Zhong Yuan, Yang Quanjun, Huang Jinlu, Li Jie, Huo Yan, Zhao Yuwu, Wan Lili, Guo Cheng

Abstract excerpt

AIM: It is reported that ABCA1, which plays a key role in cholesterol transport and apolipoprotein E (APOE) metabolism in the brain, is related to Alzheimer's disease. However, few studies have focused on the relationship between the ABCA1 gene and the therapeutic response to donepezil (DNP), which has been shown to be related to reduced sAPP production.This study evaluated the association between the ABCA1 gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29605487
DOI: 10.1016/j.brainresbull.2018.03.014

Genes

ABCA1
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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