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Article

Common formin-regulating sequences in Smy1 and Bud14 are required for the control of actin cable assembly in vivo.

Molecular biology of the cell - 1 Mar 2016

Eskin Julian A, Rankova Aneliya, Johnston Adam B, Alioto Salvatore L, Goode Bruce L

Abstract excerpt

Formins comprise a large family of proteins with diverse roles in remodeling the actin cytoskeleton. However, the spatiotemporal mechanisms used by cells to control formin activities are only beginning to be understood. Here we dissected Smy1, which has dual roles in regulating formins and myosin. Using mutagenesis, we identified specific sequences in Smy1 critical for its in vitro inhibitory effects on the FH2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26764093
DOI: 10.1091/mbc.E15-09-0639
PMCID: PMC4803308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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