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Article

Molecular Analysis of the RET Proto-Oncogene Key Exons in Patients with Medullary Thyroid Carcinoma: A Comprehensive Study of the Iranian Population

10 Feb 2011

Abstract excerpt

BACKGROUND: Germ-line mutations of RET proto-oncogene are the known cause of hereditary medullary thyroid carcinoma (MTC), which account for approximately 25% of all MTC cases and occur as multiple endocrine neoplasia type 2 syndromes. Here, we present the first comprehensive genetic screening and analysis of MTC among Iranian families. METHODS: A total of 55 patients with MTC (male to female ratio=1:1.6; average...

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Identifiers

PMID: 21309721
DOI: 10.1089/thy.2010.0267

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Molecular Analysis of the RET Proto-Oncogene Key Exons in Patients with Medullary Thyroid Carcinoma: A Comprehensive Study of the Iranian PopulationPMID 21309721Read ↗

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