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Article

Genetic Influence on the Peripheral Blood CD4+ T-cell Differentiation Status in CMV Infection.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Dec 2016

Goldeck David, Larsen Lisbeth Aagaard, Christiansen Lene, Christensen Kaare, Hamprecht Klaus, Pawelec Graham, Derhovanessian Evelyna

Abstract excerpt

A latent infection with cytomegalovirus (CMV), a ubiquitous beta herpesvirus, is associated with an accumulation of late-differentiated memory T-cells, often accompanied by a reciprocal reduced frequency of early-differentiated cells (commonly also referred to as "naïve"). However, this impact of CMV on T-cell phenotypes is variable between individuals. Our previous findings in a subgroup of participants in the...

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Identifiers

PMID: 26755680
DOI: 10.1093/gerona/glv230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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