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Article

Hallmark Features of Immunosenescence Are Absent in Familial Longevity

20 Sept 2010

Abstract excerpt

Seropositivity for CMV is one of the parameters of the "immune risk profile" associated with mortality in longitudinal studies of the very elderly and may accelerate immunosenescence. Thus, any genetic factors influencing human longevity may be associated with susceptibility to CMV and CMV-accelerated immunosenescence. To test this, we analyzed long-lived families in the Leiden Longevity Study (LLS) in which...

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PMID: 20855876
DOI: 10.4049/jimmunol.1001629

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