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Article

Induction of protein translation by ADAR1 within living cell nuclei is not dependent on RNA editing.

Molecular cell - 1 Nov 2002

Herbert Alan, Wagner Stefan, Nickerson Jeffrey A

Abstract excerpt

Translation of mRNA is usually cytoplasmic. We report that the RNA editing enzyme ADAR1, which catalyzes the deamination of adenosine to inosine in double-stranded RNA substrates, induces translation within the nucleus, possibly at the surface of the nucleolus. This activity does not depend on RNA editing. Two regions within ADAR1 are defined that act independently of each other to induce translation: the first...

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Identifiers

PMID: 12453429
DOI: 10.1016/s1097-2765(02)00737-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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