Article
Glucose repression of the yeast ADH2 gene occurs through multiple mechanisms, including control of the protein synthesis of its transcriptional activator, ADR1.
Molecular and cellular biology - 1 Apr 1992
Vallari R C, Cook W J, Audino D C, Morgan M J, Jensen D E, Laudano A P, Denis C L
Abstract excerpt
The rate of ADH2 transcription increases dramatically when Saccharomyces cerevisiae cells are shifted from glucose to ethanol growth conditions. Since ADH2 expression under glucose growth conditions is strictly dependent on the dosage of the transcriptional activator ADR1, we investigated the pos...
Topics
- Alcohol Dehydrogenase
- Binding Sites
- DNA-Binding Proteins
- Enzyme Repression
- Ethanol
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Glucose
- Mutation
- Phosphorylation
- Protein Biosynthesis
- RNA, Messenger
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins