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Article

ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis

11 Jan 2016

Abstract excerpt

Aldehyde dehydrogenase 1A1 (ALDH1A1) and ALDH3A1 are corneal crystallins. They protect inner ocular tissues from ultraviolet radiation (UVR)-induced oxidative damage through catalytic and non-catalytic mechanisms. Additionally, ALDH3A1 has been postulated to play a regulatory role in the corneal epithelium based on several studies that report an inverse association between ALDH3A1 expression and corneal cell...

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PMID: 26751691
DOI: 10.1371/journal.pone.0146433

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