Article
Gene Silencing and Haploinsufficiency of Csk Increase Blood Pressure.
PloS one - 1 Jan 2016
Lee Hyeon-Ju, Kang Ji-One, Kim Sung-Moon, Ji Su-Min, Park So-Yon, Kim Marina E, Jigden Baigalmaa, Lim Ji Eun, Hwang Sue-Yun, Lee Young-Ho, Oh Bermseok
Abstract excerpt
OBJECTIVE: Recent genome-wide association studies have identified 33 human genetic loci that influence blood pressure. The 15q24 locus is one such locus that has been confirmed in Asians and Europeans. There are 21 genes in the locus within a 1-Mb boundary, but a functional link of these genes to blood pressure has not been reported. We aimed to identify a causative gene for blood pressure change in the 15q24...
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