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Article

miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1

8 Jan 2016

Abstract excerpt

UNLABELLED: miRNAs have important roles in regulating cancer stem cell (CSC) properties and are considered to be potential therapeutic targets. However, few studies have focused on miRNAs which are specifically related to colon CSCs. Here, a PCR-based miRNA profiling analysis of normal colon stem cells (NCSC) and colon CSCs (EpCAM⁺/CD44⁺/CD66a⁻) identified miRNAs which regulate colon CSC properties....

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Identifiers

PMID: 26747706
DOI: 10.1158/1541-7786.mcr-15-0380

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miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1PMID 26747706Read ↗

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The recently suggested intestinal cancer stem cell marker<i>DCLK1</i>is an epigenetic biomarker for colorectal cancerSemantic proximity Read ↗

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