Article
Pleiotropic effects of DCLK1 in cancer and cancer stem cells
26 Sept 2022
Abstract excerpt
Doublecortin-like kinase 1 (DCLK1), a protein molecule, has been identified as a tumor stem cell marker in the cancer cells of gastrointestinal, pancreas, and human colon. DCLK1 expression in cancers, such as breast carcinoma, lung carcinoma, hepatic cell carcinoma, tuft cells, and human cholangiocarcinoma, has shown a way to target theDCLK1gene and downregulate its expression. Several studies have discussed the...
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