Article
Determining the effects and challenges of incorporating genetic testing into primary care management of hypertensive patients with African ancestry.
Contemporary clinical trials - 1 Mar 2016
Horowitz C R, Abul-Husn N S, Ellis S, Ramos M A, Negron R, Suprun M, Zinberg R E, Sabin T, Hauser D, Calman N, Bagiella E, Bottinger E P
Abstract excerpt
People of African ancestry (Blacks) have increased risk of kidney failure due to numerous socioeconomic, environmental, and clinical factors. Two variants in the APOL1 gene are now thought to account for much of the racial disparity associated with hypertensive kidney failure in Blacks. However, this knowledge has not been translated into clinical care to help improve patient outcomes and address disparities....
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