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Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model

11 Jan 2016

Abstract excerpt

Advancement of many solid tumors and hematologic malignancies is frequently characterized by dissemination and homing of cancer cells to the bone marrow (BM). Methods to quantitatively characterize these key steps of the metastatic cascade in mammalian models are currently limited and do not offer opportunities to perform rapid, large-scale genomic, or drug screening. Because of their optical clarity, we used...

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PMID: 26744527
DOI: 10.1158/0008-5472.can-15-1926

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