Article
Prognostic significance of L1CAM expression and its association with mutant p53 expression in high-risk endometrial cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2016
Van Gool Inge C, Stelloo Ellen, Nout Remi A, Nijman Hans W, Edmondson Richard J, Church David N, MacKay Helen J, Leary Alexandra, Powell Melanie E, Mileshkin Linda, Creutzberg Carien L, Smit Vincent T H B M, Bosse Tjalling
Abstract excerpt
Studies in early-stage, predominantly low- and intermediate-risk endometrial cancer have demonstrated that L1 cell adhesion molecule (L1CAM) overexpression identifies patients at increased risk of recurrence, yet its prognostic significance in high-risk endometrial cancer is unclear. To evaluate this, its frequency, and the relationship of L1CAM with the established endometrial cancer biomarker p53, we analyzed...
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