Article
L1 cell adhesion molecule (L1CAM) in invasive tumors.
Cancer letters - 18 Sept 2009
Raveh Shani, Gavert Nancy, Ben-Ze'ev Avri
Abstract excerpt
The L1 cell adhesion molecule (L1CAM) belongs to the immunoglobulin superfamily and was originally identified in the nervous system. Recent studies demonstrated L1CAM expression in various types of cancer, predominantly at the invasive front of tumors and in metastases, suggesting its involvement in advanced stages of tumor progression. Overexpression of L1CAM in normal and cancer cells increased motility,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
