Article
Particular molecular and ultrastructural aspects in invasive mammary carcinoma.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2015
Mihalcea Corina Elena, Moroşanu Ana Maria, Murăraşu Daniela, Puiu Liliana, Cinca Sabin, Voinea Silviu Cristian, Mirancea Nicolae
Abstract excerpt
Electron microscopic investigations of invasive mammary carcinoma tumors revealed that intercellular junctions, namely desmosomes are severely altered; some desmosomes became internalized. Tumor cells, especially by their invadopodia, generate and disseminate membrane vesicles, including exosomes, inside of peritumoral stroma. Telocytes, a new described interstitial/stromal cell phenotype, considered to play...
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