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Article

MicroRNA-150 Suppression of Angiopoetin-2 Generation and Signaling Is Crucial for Resolving Vascular Injury.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2016

Rajput Charu, Tauseef Mohammad, Farazuddin Mohammad, Yazbeck Pascal, Amin Md-Ruhul, Avin Br Vijay, Sharma Tiffany, Mehta Dolly

Abstract excerpt

OBJECTIVE: Increased vascular permeability is a hallmark of sepsis and acute respiratory distress syndrome. Angiopoietin (Ang2) induces vascular leak, and excess Ang2 generation is associated with patient mortality from these diseases. However, mechanisms dampening Ang2 generation during injury remain unclear. Interestingly, microRNA (miR)-150 levels were decreased in septic patients. miR regulate signaling...

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Identifiers

PMID: 26743170
DOI: 10.1161/ATVBAHA.115.306997
PMCID: PMC4732888

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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