Article
A conserved long noncoding RNA, GAPLINC, modulates the immune response during endotoxic shock
10 Feb 2021
Abstract excerpt
Significance Inflammation has largely been studied in the context of protein-coding genes. Recent studies have uncovered lncRNAs as important regulators of immunity. The functional characterization of these genes remains an active area of research. In this study, we identify GAPLINC as a functionally conserved lncRNA between human and mouse. GAPLINC depletion results in enhanced expression of immune response...
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