Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The structure and DNA-binding properties of Mgm101 from a yeast with a linear mitochondrial genome.

Nucleic acids research - 18 Mar 2016

Pevala Vladimír, Truban Dominika, Bauer Jacob A, Košťan Július, Kunová Nina, Bellová Jana, Brandstetter Marlene, Marini Victoria, Krejčí Lumír, Tomáška Ľubomír, Nosek Jozef, Kutejová Eva

Abstract excerpt

To study the mechanisms involved in the maintenance of a linear mitochondrial genome we investigated the biochemical properties of the recombination protein Mgm101 from Candida parapsilosis. We show that CpMgm101 complements defects associated with the Saccharomyces cerevisiae mgm101-1(ts) mutation and that it is present in both the nucleus and mitochondrial nucleoids of C. parapsilosis. Unlike its S. cerevisiae...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Candida
Share to DNA, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Fungal

Share to Genome, Mitochondrial

Share to Mitochondrial Proteins

Share to Protein Multimerization

Share to Telomere

Share to Telomere Homeostasis

Source

Open in PubMed Open full text

Identifiers

PMID: 26743001
DOI: 10.1093/nar/gkv1529
PMCID: PMC4797282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The structure and DNA-binding properties of Mgm101 from a yeast with a linear mitochondrial genome.PMID 26743001Read ↗

Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination.Semantic proximity Read ↗

Complete DNA sequences of the mitochondrial genomes of the pathogenic yeasts Candida orthopsilosis and Candida metapsilosis: insight into the evolution of linear DNA genomes from mitochondrial telomere mutants.Semantic proximity Read ↗

The N-terminal intrinsically disordered domain of Mgm101p is localized to the mitochondrial nucleoid.Semantic proximity Read ↗

Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA.Semantic proximity Read ↗

A functional core of the mitochondrial genome maintenance protein Mgm101p in Saccharomyces cerevisiae determined with a temperature-conditional allele.Semantic proximity Read ↗

MGM101, a nuclear gene involved in maintenance of the mitochondrial genome in Saccharomyces cerevisiae.Semantic proximity Read ↗

The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG-related disorders.Semantic proximity Read ↗

A non-radioactive DNA synthesis assay demonstrates that elements of the Sigma 1278b Mip1 mitochondrial DNA polymerase domain and C-terminal extension facilitate robust enzyme activity.Semantic proximity Read ↗

Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.Semantic proximity Read ↗

Mitochondrial genome variability within the Candida parapsilosis species complex.Semantic proximity Read ↗

Yeast model analysis of novel polymerase gamma variants found in patients with autosomal recessive mitochondrial disease.Semantic proximity Read ↗

Structure-Guided Mutations in the Terminal Organelle Protein MG491 Cause Major Motility and Morphologic Alterations on Mycoplasma genitalium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.