Article
Structure-Guided Mutations in the Terminal Organelle Protein MG491 Cause Major Motility and Morphologic Alterations on Mycoplasma genitalium.
PLoS pathogens - 1 Apr 2016
Martinelli Luca, García-Morales Luis, Querol Enrique, Piñol Jaume, Fita Ignacio, Calisto Bárbara M
Abstract excerpt
The emergent human pathogen Mycoplasma genitalium, with one of the smallest genomes among cells capable of growing in axenic cultures, presents a flask-shaped morphology due to a protrusion of the cell membrane, known as the terminal organelle, that is involved in cell adhesion and motility and is an important virulence factor of this microorganism. The terminal organelle is supported by a cytoskeleton complex of...
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