Article

Identifying Potential Novel Pathways and Therapeutic Targets of Major Depressive Disorder with Functional Genomics

2021-03-31

Abstract excerpt

<h4>Background: </h4> Major depressive disorder (MDD) is a debilitating illness and a leading cause of disability, but its pathophysiology remains to be completely elucidated. Resistance to traditional antidepressant treatment is highly prevalent within patient populations. Ketamine, a rapid-acting antidepressant that has shown success in treating resistant patients, is hypothesized to function by modulating excit...

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Literature Corpus work: cde9c2fd-1498-5e59-bad3-a4b95a80b377
DOI: 10.21203/rs.3.rs-374465/v1

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