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Article

Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study.

Scientific reports - 4 Jan 2016

Reddon Hudson, Gerstein Hertzel C, Engert James C, Mohan Viswanathan, Bosch Jackie, Desai Dipika, Bailey Swneke D, Diaz Rafael, Yusuf Salim, Anand Sonia S, Meyre David

Abstract excerpt

Physical activity (PA) has been shown to reduce the impact of FTO variation and obesity genetic risk scores (GRS) on BMI. We examined this interaction using a quantitative measure of PA and two adiposity indexes in a longitudinal multi-ethnic study. We analyzed the impact of PA on the association between 14 obesity predisposing variants (analyzed independently and as a GRS) and baseline/follow-up obesity measures...

Topics

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Body Mass Index
Ethnicity
Follow-Up Studies
Longitudinal Studies
Motor Activity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Patient Outcome Assessment

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Open in PubMed Open full text

Identifiers

PMID: 26727462
DOI: 10.1038/srep18672
PMCID: PMC4698633

Genes

FTO
BDNF
CDKAL1
GIPR
NPC1
NTRK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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