Five-Year Survival in EGFR-Mutant Metastatic Lung Adenocarcinoma Treated with EGFR-TKIs.

doi:10.1016/j.jtho.2015.12.103

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Article

Five-Year Survival in EGFR-Mutant Metastatic Lung Adenocarcinoma Treated with EGFR-TKIs.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2016

Lin Jessica J, Cardarella Stephanie, Lydon Christine A, Dahlberg Suzanne E, Jackman David M, Jänne Pasi A, Johnson Bruce E

Abstract excerpt

INTRODUCTION: Activating mutations in the epidermal growth factor receptor gene (EGFR) predict for prolonged progression-free survival in patients with advanced non-small cell lung cancer (NSCLC) treated with EGFR tyrosine kinase inhibitors (EGFR-TKIs) versus chemotherapy. Long-term survival outcomes, however, remain undefined. The objective of this study was to determine the 5-year survival in these patients and...

Topics

Adenocarcinoma
Adenocarcinoma of Lung
Adult
Aged
Aged, 80 and over
Antineoplastic Agents
ErbB Receptors
Female
Humans
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Massachusetts

Middle Aged

Mutation

Neoplasm Metastasis

Protein Kinase Inhibitors

Randomized Controlled Trials as Topic

Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 26724471
DOI: 10.1016/j.jtho.2015.12.103
PMCID: PMC4979601

Genes

EGFR

Provenance

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