Article
Activating mutations within the EGFR kinase domain: a molecular predictor of disease-free survival in resected pulmonary adenocarcinoma.
Journal of cancer research and clinical oncology - 1 Dec 2009
Lee Young Joo, Park In Kyu, Park Moo-Suk, Choi Hye Jin, Cho Byoung Chul, Chung Kyung Young, Kim Se Kyu, Chang Joon, Moon Jin Wook, Kim Hoguen, Choi Sung Ho, Kim Joo-Hang
Abstract excerpt
PURPOSE: Although epidermal growth factor receptor (EGFR) tyrosine kinase (TK) mutations are highly predictive of response to EGFR TK inhibitors in advanced non-small-cell lung cancer (NSCLC), a prognostic value of EGFR mutations in resected NSCLC has not been established. METHODS: We retrospectively reviewed 117 patients with primary lung adenocarcinoma who underwent surgical resection between 1995 and 2005....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
