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Article

Cell surface heparan sulfate proteoglycans as novel markers of human neural stem cell fate determination

18 Dec 2015

Abstract excerpt

Multipotent neural stem cells (NSCs) provide a model to investigate neurogenesis and develop mechanisms of cell transplantation. In order to define improved markers of stemness and lineage specificity, we examined self-renewal and multi-lineage markers during long-term expansion and under neuronal and astrocyte differentiating conditions in human ESC-derived NSCs (hNSC H9 cells). In addition, with proteoglycans...

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PMID: 26722758
DOI: 10.1016/j.scr.2015.12.011

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