Article
Genetic polymorphisms of the TNF-α-308G/A are associated with metabolic syndrome in asthmatic patients from Hebei province, China.
International journal of clinical and experimental pathology - 1 Jan 2015
Yang Yong-Hui, Liu Yan-Qin, Zhang Ling, Li Hui, Li Xing-Bin, Ouyang Qin, Zhu Gui-Yun
Abstract excerpt
Asthma is a complex inflammatory disease involving the critical actions of several important cytokines. Epidemiological data show that obesity could increase the risk of asthma, and insulin resistance, or metabolic syndrome are an important risk factor for obesity asthma. Some studies identified that upstream of the transcription start site within the TNF-α gene promoter region-308 polymorphism was associated...
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