Article
CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America - 12 Jan 2016
Toya Mika, Kobayashi Saeko, Kawasaki Miwa, Shioi Go, Kaneko Mari, Ishiuchi Takashi, Misaki Kazuyo, Meng Wenxiang, Takeichi Masatoshi
Abstract excerpt
Polarized epithelial cells exhibit a characteristic array of microtubules that are oriented along the apicobasal axis of the cells. The minus-ends of these microtubules face apically, and the plus-ends face toward the basal side. The mechanisms underlying this epithelial-specific microtubule assembly remain unresolved, however. Here, using mouse intestinal cells and human Caco-2 cells, we show that the...
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