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Article

Uncommon TERT Promoter Mutations in Pediatric Thyroid Cancer.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2016

Alzahrani Ali S, Qasem Ebtesam, Murugan Avaniyapuram Kannan, Al-Hindi Hindi N, AlKhafaji Dania, Almohanna Mai, Xing Mingzhao, Alhomaidah Doha, AlSwailem Meshael

Abstract excerpt

PURPOSE: The aim of this study was to determine the rate and significance of TERT promoter mutations that have been recently described in adult thyroid cancer (TC) but not yet in the uncommonly occurring pediatric TC. Furthermore, the role of the BRAF(V600E) mutation in the clinical outcome of pediatric TC is unknown. METHOD: The study included 55 pediatric (median age 16 years, range 9-18 years; 46 females) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Recurrence, Local

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins B-raf

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Share to Thyroid Neoplasms

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Source

Identifiers

PMID: 26711586
DOI: 10.1089/thy.2015.0510

Genes

BRAF
TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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